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Disclaimer- The information provided here is for educational purposes, I am not a medical professional nor a genetics professional. While I can describe some of the things I have learned and researched, each individual is different and what worked for me may not work for you.

About SNPedia

SNPedia: http://www.snpedia.com/index.php/SNPedia This is a wiki site with a ton of information on SNP's (Single Nucleotide Polymorphism (SNP, pronounced snip; plural snips). The best way is to use the search box in the upper right corner, with either the RS number or the Gene name, like MTHFR. It is a work in progress where links to recent research can be found, also stats on population percentages for homozygous, heterozygous or normal homozygous. SNPedia was recently acquired by MyHeritage.

An example would be looking up the gene MTHFR: http://www.snpedia.com/index.php/MTHFR

Or one of the problem SNP's like MTHFR C677T, with RS number, rs1801133: http://www.snpedia.com/index.php/Rs1801133

For this SNP, the CC would be homozygous normal, the CT is heterozygous and the TT is homozygous for the minor allele. Note the way this is written, as C677T. The C would be the normal configuration, the T is the mutation.

As a general rule, it is the homozygous configuration with the least population, the minor allele, that is the problem one. This does not mean all homozygous snp's in the lower populations are bad, the majority are just normal genetic variations. There are exceptions to this rule where you will find that the more common homozygous configuration, present in most of the population, is the least desired one because the more rare mutation confers some type of protection against a commom disease.

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