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Disclaimer- The information provided here is for educational purposes, I am not a medical professional nor a genetics professional. While I can describe some of the things I have learned and researched, each individual is different and what worked for me may not work for you.

Thinking out loud

Introduction

2015. This website will be ad free, at least for the moment and I hope to never have to go there. I despise the constant, in your face advertising, tracking cookies, and assorted other "cool" contraptions that can be added to a website for the specific purpose of gathering and selling information. I am still learning the behind the scene things that go on and although I would like to add some of these options, I can't bring myself to do it after reading the fine print. It all seems to be about selling information to those invisible third parties.

I work full time and have limited time to devote to this project so it will take me a while to build this site. I am researching and covering many subjects, still learning and taking in new information as well. There is only so much time in a day and still so much to learn. Life long learning is a passion of mine, my mind is constantly going and I figured out years ago that if I don't focus it on constructive and interesting projects, I will soon get in trouble.

December 29, 2019

Recent changes to Genomic Resources.

Recently there have been some discouraging developments in the promising world of genomics exploration and tools.

As of December 2019, GEDmatch has been bought by Verogen, Inc, a forensic genomics company. Please be sure to read the privacy statement and options as this company is using the available genomic data from GEDmatch for criminal investigations. You can opt in or out participation with law enforcement but be aware that this was already violated when owned by GEDmatch, when presented with a warrant in one case that allowed law enforcement access to all data regardless of opting in or out. I have deleted all information on GEDmatch as my genomic information is not for sale.

The second item that was very discouraging was the acquisition of Promethease and SNPedia by MyHeritage, an Israeli company. MyHeritage is a popular genealogy website and like several others allow people to upload their genome for genealogical purposes. I don’t have an issue with that purpose. The problem I have is I have not opted into having my genome used by MyHeritage for health research which is the only logical reason it would acquire Promethease and SNPedia as both are geared toward understanding health issues. I had both my 23andMe and Whole Exome tests uploaded to Promethease, they have the 23andMe test already. Given that the Whole Exome test is much more extensive, I do not want that available to whomever. My Whole Exome test is not for sale, they did not pay for it and have no right to my information and so both were deleted.

What a deal, you can now just purchase the genomic information of hundreds of thousands of people and expand your database without anyone giving consent prior to it. As with GEDmatch, you can opt in or out of having your information saved. I would still recommend using Promethease, just not saving the information for them to use.

January 6, 2019

It’s the Sugar, stupid.
I am posting this for all the people out there who may have unidentified problems with Hypoglycemia. Some background for you. 3 generations of my family, all women, have problems with Hypoglycemia, you know that rare problem if you are not diabetic, according to all the Medical establishment. We are not diabetic but that does run in the family and I can see why. If our particular variation of this was not managed well we could definitely end up there as every time the blood sugar crashes, we have to eat. The choice of what to eat and how much is very important. If it crashes hard we have no choice but to eat some sugars to bring it back up quickly but too much sugar or refined carbs (not complex carbs) and we just end up at the same point again with the blood sugar crashing, over and over, and over. It would be extremely easy to overeat in this situation, pack on the weight, end up with metabolic syndrome or worse, diabetes. I have a somewhat physical job and for me hypoglycemia has occurred 4 times a day at work, basically every two hours outside of eating lunch, for 38 years. It is somehow related to my muscles, the harder I work, the more I struggle to keep the blood sugar levels up. Then I get the adrenaline rush that stings my face, makes me break out in a sweat, get ravenously hungry, the brain goes off line and I can’t think, talk or drive a car, if it is bad enough my legs get weak and feel like they will come out from underneath me but they will still work.

It totally sucks. When I read that diabetics may have a few episodes of hypoglycemia a week, I feel for them, at least I don’t have to take insulin and possibly overshoot the margin of safety. They dread this more than anything and it is considered a medical emergency. But when I have this problem, 365 days of the year and 4 times a day, it is hard to understand why I get nothing but blank stares from every doctor I have seen when I mention it. No answers, no testing, no response period. It is reproducible and never goes away.

This is the primary reason I got into genetics testing. I wanted the answers I cannot seem to get. I expected this problem to show up #1 on the top of my list of pathogenic mutations but still it is nowhere to be found, more than likely it is just not known about as I have some mutations that could be contributors but nothing is known about them. We have the general risks for diabetes along with half the population. I have one listed as pathogenic for diabetes, MODY, the description states that one will likely have diabetes by early adulthood, maybe later but we don’t.

Our problem does kick in around the age of 20 but does not automatically mean that we suddenly become insulin resistant like the gene description states. No family member has had that problem. I have several fasting blood tests from doctors where my glucose levels are 62, 65, the average is about 71 and I take the test before 10 am as I cannot wait til later. The one that was 62 was about 10am and by the time I got out of the blood draw clinic, I crashed and had to get something to eat, pronto. I usually take a snack bar with me anywhere I go because of this. I looked at using the glucose tablets that diabetics use to bring their sugar levels back up but these are fast acting sugars, which for me is the problem.

We cannot eat sugars or some refined carbs without it dropping our blood glucose level. This includes any fast burning sugar like honey, maple syrup, fruits, fruit juices (I consider fruit juice to be a sugar IV, just dump sugar straight into my system), cake icings, sugar, sodas, ice cream, some coffee drinks, most commercially produced breakfast foods and bakery items. In other words about 90% of the food in a grocery store is off limits for us and everyone is scratching there heads wondering where this diabetes epidemic is coming from. I cannot eat/take, cinnamon or CoQ10 as these drop my blood sugar levels and affect me for a couple of days which I don’t understand, as insulin has a short half life. I have searched high and low, studied the complex biochemical pathways from the top to the bottom and there are a lot of areas that could affect the blood glucose levels. I have looked at hyperinsulinism (mostly ruled out), glycogen storage disease (not completely ruled out although there are no known genes in my genetics), I have looked at insulin receptors, glucagon deficiency, somatostatin, alpha and beta cells of the pancreas, areas that produce glucose for compensation in blood sugar drops like the liver, kidneys and intestines and all the genes related to this. Nothing stands out from known pathogenic mutations. Actually, it does not look quite like any of the known issues. So, back to the drawing board in my quest to get off the rollercoaster.

I recently got really fed up with the whole issue and over a weekend broke down my diet into component parts. I found a really useful app that separates the carbs from the sugars by Jommi UG, there are 3 apps, I bought the 3 app package for about $5 US. They are called CalorieGuide, CG Restaurant and Supermarket. There are surprisingly few apps that even consider the two things as different and I can tell you that they are very different in how the body reacts to carbs vs sugars as we are super sensitive to this. Complex carbs don’t jerk my blood sugar around, seems my body is OK with the glucose made internally from the conversion of complex carbs and proteins to glucose. I found out potatoes and rice, you know the things they tell you to stay away from, they have no sugar at all, I have no issue with them. It is a whole different story when I eat glucose, fructose, anything that is straight simple sugars, even refined flours, anything that metabolizes quickly. Sugars don’t make us sick as in fructose intolerance, it just that we pay for it later with crashing blood sugar levels. I will mention that I can get away with eating small amounts of a cake or brownies and the like (without icing) if it is eaten at the same time as a large meal with proteins, fats and carbs.

What I found out by breaking down my diet was that all totaled I was ingesting about 40 grams of sugars a day. I knew about where the threshold was but this exercise made it much more clear and I knew that was too much as it is close to the amount of sugars in a can of soda pop and I cannot drink those. I reduced the sugar even more in the small muffins I make for breakfast. I made sure the fruit cup I eat at lunch was drained of syrup rather than just picking out the fruit with a fork. I tried to find an alternative to my afternoon snack as it has 14 grams of sugars (14 grams is 3.29 teaspoons, too much) and this is my upper limit for eating sugars at one time. Reducing the sugar in the muffin to about 8 grams each helped quite a bit.

I am finding right now that if I eat no more than 10 grams at a time with no more than 30 grams per day, my blood sugar actually stays higher than it has ever been. I am pretty sure if I could eliminate all sugars, I would no longer have any issue with hypoglycemia. I had to work my way slowly down reducing a little sugar here, some there. I am using a glucose meter to measure blood sugars as I am not really sure where it is landing now that it is not crashing all the time. Just want to make sure there is no rebound in the other direction. Still I have the issue with keeping blood sugar up when doing physical work but it much more manageable than it was a year ago.

October 29, 2017

Her Name is Asemiah Gertrude Maffet (Moffit). Born 3 May, 1822, died 13 April 1872. She married James C. Adams about 1842.
Finally, after years of looking for my GGGG grandmother’s last name, her real name actually, I have found it. Not expecting more than that and thinking I would have to fight for the next step in that family line, I found her entire family listed in a history of York County Pennsylvania. Although I could write about what I found, I have linked the original text and the extracted pages that are relevant as the book is a large file that will be too much for some internet connections. New informaton is presented on the Adams family page.

I found her original name on the death certificate for her daughter Clara. My Aunt provided a better picture of her, which I restored in photoshop and posted. She also provided obituaries and another photo that has the company name in York, PA. This company, Seeling and Evans, was only operating in York, PA from 1860-1862. We don’t know why she went back at this time as her and James were living in Ohio with a young child. By this time her parents have passed away although one brother, James was operating a grain mill, grinding various flours in a nearby township at Muddy Creek Forks in PA. His sons picked up the business later and ran it for many years.

Asemiah G. Maffet married James C. Adams, their children are Calvin Simpson Adams, Martha Jane Adams, Allen Dustin Adams and Clara L. Adams (Sample). Both Asemiah and James were born in Pennsylvania, later moving to Lisbon, Ohio where their children were born, then moving again to Harrison township, the county of Miami in Indiana before the 1870's. James was buried May 1873 in Peoria, Miami county Indiana. Asemiah died in Indiana but was buried with 3 infants in Lisbon, Ohio. I am fairly sure she is buried in the Lisbon Village Cemetery. For Maffet family genealogy paper I put together with some additional information not found in the book, go here.

June 27, 2017

Just got done verifying the Cocke line from Virginia. I had no idea that our family roots went so deep back in time to the prominent families of Virginia. There are so many Revolutionary war leaders that I would not be able to pick one if I wanted to apply for something like DAR.

Digging deeper into Genomics has taught me a lot but there are several pitfalls to the information that is posted on the web as to which SNP’s might be disease causing. It is hard to find a solid study to believe as most are so limited in the number of participants. I can recall a few years back, that many researchers jumped all over the 1000 genome project and started assigning certain fairly common SNP’s to certain disorders. Some of those have already been retracted and are now considered benign. I don’t know how you can take the genomes of 1000 people, divide that up among various populations and come out with any meaningful information. Myself, I have a couple thousand rare mutations (under 1 percent), most that won’t amount to anything significant, with a large percentage (most) that nothing is known about. Now that they are starting to list up to 121,000 people or so in the population database of dbsnp, there is at least some population information available on some of them. Nice to know that someone besides me has that same mutation. This brought up the question of how rare are rare mutations? I could only find a couple of articles on the web that didn’t really answer that question other than to say rare mutations may not be as rare as they thought. I am sure that we will get a better picture as time goes on and more information is added.

I went ahead and took a Whole Exome test. That is a lot of information to dig through even though they only post most mutations that are known to cause disease or are suspect mutations. I will not mention the company as I cannot recommend it. The price was right and I got the information but it was difficult to use the format that they advertise as being easily portable to your doctor or health care professional. I beg to differ in how easy it would be for a doctor to take that information and find software that could put it in an intelligible presentation. Most doctors don’t even know about nutrition let alone how to use genomic software that the researchers use. This company used a .vcf format which is standard for Exome testing but with some twists they added to the format as there is no standard .vcf format. The good folks at Enlis Genomics helped me in the conversion so I could use their software but said this format would likely not be supported by them. I found out over the last 6 months, just how difficult it is trying to navigate the various formats available as nothing is standardized. The genomics field is starting to get around to some type of standardization but it is not there yet. That said, I found a few more resources that can be used for the serious explorer and I will post these.

December 28, 2016

I just posted some information about Enlis Genomics.
Their software is free and it is the file processing that costs. What I like about this software is that I don’t have to think about whether the orientation is on the forward or reverse strand, especially on the C to G type of conversions. They report everything on the forward or plus strand.
Enlis will let you process the file for free with a short report sent to you and a link back to pay and get the whole thing. It is a kind of teaser really but if you want to see short sample before you buy, it is a nice option.

Here is their reply to my question as to strand orientation: “The reason that Promethease and others run into strand conversion problems is that they use the dbSNP rsid to import a SNP.  As you may have discovered on your own, dbSNP can be a messy database, and database entries and be either on the + or - strand of the human reference genome. We don't use the dbSNP rsid.  For importing data, we use the chromosome location.  And since 23andMe reports the data on the plus stand, there is no need for conversion.”

Enlis Genomics went thru the free online 23andMe files posted by people and reverse engineered the internal numbers, the ones that start with an “i“instead of “rs”, based on chromosomal locations and pulled out a lot more information from the 23 and me file. They also removed what they consider “over calls” of certain snps which are found in 23andMe raw data. This is where the number of reported mutations for a certain disorder are way out of the norm in relation to the population data and are probably errors. See the info under Genetics and Resources.

October 23, 2016

I have been thinking a lot about diet and after 4 years of experimentation with food, I can say that the only diet I will ever advocate is an Ancestral diet. We have longevity genes and a surprising number of relatives lived to 80 years old or more without copious salads doused in soy oil. They ate grains, meat, soups, fat, fruits and vegetables but I would think they did not have much sugar, definitely not high fructose corn syrup. There were not highly process grains that were sprayed with Roundup. If you look at most frozen or boxed meals they are all wheat, dairy or rice based with a touch of some meat, maybe a veggie thrown in. Has anyone but me noticed the change in body type from the 1970’s until now. Go watch some 1970’s movies, people were generally slim and fit. Now look at people today, overweight, pale, with a pasty-doughy look to their skin. I am talking in broad generalities but a significant portion of the population is not well. What changed? Soy in the diet was all but nonexistent, now it is some kind of wonder food when really it is not that good for you. We had Canola and Corn oil before it was bastardized by GMO modifications. Most meals were home cooked. Visit Walmart, we now have whole rows at the grocery store for just cereal, another row for cookies and crackers, another row for just chips. 2 of those rows are nothing but wheat and sugar. Guess how much space the canned fruits, vegetables and things like tomato sauce take up, maybe one row combined. Oh, there is also an entire row for bread type foods, more wheat. It strikes me that the composition of our grocery stores adequately reflects the composition of our diets today. I will not even approach the subject of the Fast Food industry. Our food in the 70’s was not filled with exotic sounding chemical substitutes for real ingredients. We ate meat, bread, cheese, milk, veggies (canned or fresh), fruits and rarely any salads. The food didn’t need added glutamates to enhance what is left of the flavor after processing. There were no soda machines in school, no candy bar machines everywhere and children were restricted in how much candy and sweets they ate. One thing I have discovered after going gluten free, dairy free, processed food and soy free, is the intensity of natural flavors when you cook at home from scratch. I re-discovered flavors I have not tasted in years and the bonus of getting my health back.

I am working on documentation of family lines which takes a lot time and digging. Although I have ancestors that came through the ports in New England, I am finding that more of them came through the ports in Virginia and information on those from Virginia is much less documented or has been destroyed. Oddly enough if you can get back in time to before the war for Independence in 1776, there are records as the British were fastidious record keepers and even if the local records are gone, there may be British copies.
Information on some family genealogies has been put together in older magazines that can be found on JSTOR, like The Virginia Magazine of History and Biography. I have found that some of the family histories in these old magazines are not always accurate but usually very close and still need verification. JSTOR is a subscription site for journals although some of the older publications can be found for free. You may be able to access JSTOR from a public library or university library.

23andMe just added an option for testing Ancestry only or testing for Ancestry and Health. Either way they still provide access to the raw data.

November 15, 2015
23andMe has received FDA clearance to provide Carrier status for certain genetic disorders but cannot tell you whether you are homozygous for it. I don’t really get this but it is what they state in the new material. As of this moment they have not transited from the old format to the new format but are getting close.
On another note, I purchase two books for genealogy research, they are pretty dry as they only contain genealogical lineages. I have proved out two lines so far. One being Col. John Waller of Virginia which leads to William I the Lion, King of Scotland, died 1214. The other is Thomas Trowbridge of Connecticut and Elizabeth Marshall which leads to Hugh Capet King of France, died 996. Source: The Royal Descents of 600 Immigrants to the American Colonies, 2008 by Gary Boyd Roberts.
A while back I read an article by a veteran genealogist that stated if most of your ancestors came over in the Great Migration during the 1600’s, that there is a strong possibility you would be descended from royalty. He estimated that one would have approximately 150 million cousins from these ancestors. That is almost half the population of the United States and also means that about 40-50% of the people I meet are cousins. It also means that about half of the United States are related to royalty and don’t know it. Most of my ancestors came over in the 1600’s. What a thought that is.
I also ran the Relative Finder provided by Family Search, the LDS Mormon genealogy website and found out that if my lineages are correct, I am related to several signers of the Declaration, signers of the Constitution, a Catholic Saint, European Royalty, the founders of the Mormon church and many church members, three quarters of the U.S. Presidents including the current one Barack Obama who is a 10th cousin, one time removed. George W. Bush is a 10th cousin, arrggghhh! That makes his father George H.W. Bush, a 9th cousin. JFK is a 15th cousin, boy that is going back in time quite a way. I have been able to verify several of my family lines through my cousins on 23andMe, several that go back to the 1700’s and one that goes back to about 1650. I have found the common relative we both have. Also found at the Relative Finder website, 31 cousins that were First Lady’s, wives of the Presidents. There are also 7 cousins that were involved in the Salem Witch trials, most being persecuted, 5 people that came over on the Mayflower. What a cool tool that once again shocked and astonished me with the relationships. What is nice about this tool is how it associates people that I probably would never find just looking at the primary lineage. I would have to follow all kinds of pathways through their children and their children’s children and then I might stumble upon a name I would recognize. This pulls them all right up for you. You have to have an account with FamilySearch, it is free. The top of my screen states, Showing 42/1534 relatives (I have Constitution, Declaration signers clicked on), Using 4563 ancestors and 16 generations. If you are interested visit: https://www.relativefinder.org

September 19, 2015
A few months ago while looking at the family lineages, I went down the Cave family line and realized there are 800 years of male descendants from the Cave family listed, from England to my GGG Grandmother Adeline Cave, born in 1822, died 1880. Wow! The line ends at Geoffrey DeCave, born in 1220. His son was Peter DeCave born 1253, then to Sir Knight Alexander Cave, born 1270. If you have an interest, I found this web site, The Peerage.com and did follow the Cave family line but he does not have the American ancestors listed. See: http://www.thepeerage.com/i696.htm#s9112

September 4, 2015
Food and Nutrition. I have a difficult relationship to food. I love it, would like to eat to my hearts content but can’t. I have hypoglycemia which I cannot explain where it comes from but it is a family trait, most of us have it to some extent but it does not really show up until about 20 years old. So it never gets diagnosed or the reason found because by then we know about it and just deal with it but no one in the family knows what causes it. So the sweets are out and I have a more restricted diet than diabetics as the fast burning sugars trigger and destabilize my blood sugar, sometimes for days.

I have celiac genes, the DQ2.2 version and a definite gluten intolerance. I just don’t know if I have celiac or not. I do know my reaction to wheat/barley is close enough to celiac that I don’t want to go there, so gluten is out. I will probably never know because I will not eat the required amount of bread for a month just to take the test. I did have the blood test a few months after I stopped eating wheat and realized that barley also gave me substantial brain fog and a messed up GI tract. The test was negative but if I remember correctly, the test is more geared toward reactions to wheat and DQ 2.5. I found a study that compared and tested the reactivity of 2.5 vs 2.2, there were 8 items tested and out of the 8 items, DQ2.5 reacted strongly to 5 of those substances and DQ2.2 reacted to the other 3 items more strongly. There were reactions to all 8 substances on both types of celiac genes but they did not react at the same level. DQ2.2 reacted to the same 5 substances as DQ2.5 but at a much lower level and DQ2.5 reacted to the 3 other substances that DQ2.2 reacted to strongly but at a much lower level.

I also react to dairy and had stopped drinking milk years earlier as I was able to connect my episodes of month long vertigo to milk. I was still eating cheese, love the stuff but it does not love me so that is out of my diet also. It caused strange muscle reactions and tightening of muscles as well as the fact that cheese now gives me vertigo but a milder version. Still, I tired of dealing with it for 3 or 4 months of the year and it is not worth it.

Soy, what can I say except I truly despise this stuff and it is in everything, the prepacked foods I should say. I have run across 2 other people that have reactions like I do to soy. Those reactions consist of cognitive dysfunction like looking for a item that was just set down and is right in the line of vision and it can’t be seen or maybe more accurately, recognized. Talk about waking up on the wrong side of the bed. Soy makes me anti-social, irritated and causes difficulty in focusing mentally. It makes thinking very difficult, kind of like thinking through mud. I also had difficulty with thinking that I had done something but then realize that I had only thought it, not done it. Soy is so very much out of my diet and I no longer have episodes of waking up on the wrong side of the bed. If you want an attitude problem, just eat a ton of soy. For me, it only took 1/2 teaspoon to bring on those reactions but I did not experience the problems until the next day. Lucky for me it is only a one day reaction but I hate it. I won’t go into the travesty of what is being done to our food supply by GMO’s and the residual Roundup that is even in wheat as the farmer’s use it to kill or brown up the fields at the end so everything is evenly dead for harvesting. I do know however that I react to anything that is GMO or has had Roundup sprayed on it but this does not mean it is causal, just highly suspect. I have my own opinions about this though and avoid any GMO’s like the plague as they make me sick. Yellow corn makes me ill, White corn is fine. Hmmmm. Honey is included in that as many types of honey tested had glyphosate in them. Don't believe me, check this out: Survey of Glyphosate Residues in Honey, Corn and Soy Products

Glutamates, these are also in about every prepackage food under the guise of about 30 different names because if it is not 99% glutamate, they don’t have to call it MSG. Glutamates or glutamic acid occurs naturally in many foods including meats but is found in the highest levels in Wheat, Dairy and Soy. This is another reason these foods are out of my diet. I had an amino acid test (NutrEval) that showed my glutamic acid levels were about 2 times higher than they are supposed to be. The last test, the 4th one showed glutamic acid as still too high but at least approaching high normal, three years later. If you have problems with ADD, ADHD, muscle twitching, myoclonus type activity, you might look into glutamates. There is plenty of information on the web about glutamates. If you want to read a good book about what they can do to your brain, look up Excitotoxins; The Taste that Kills by Dr. Russell L. Blaylock. Glutamates are added to food to enhance whatever residual flavor is left after proscessing wipes out most of the flavor. They excite your taste buds so the food supposedly tastes better. For some of us they bust our brains and so this too is reduced in my diet and I hardly ever buy processed foods because they are land mines full of all the problem foods listed above.

Oxalates, these are nasty little crystals created by most plants that we eat. They are part of the plants defense system as are polyphenols which I also react to. You probably have heard about the Green Smoothies fad diet. I will flat out say this, it is not a good idea for anyone with kidney disease or problems with kidney stones to eat a ton of green veggies in whatever form. That said, not all veggies are the same in oxalate content, some of the foods with the highest levels are the ones touted as the healthiest, like Chard, Chocolate, Beets, Rhubarb, Spinach, Whole Wheat, Brown rice and Almonds. In order to digest and break them down you need a type of gut bacteria but it might have been wiped out by excessive use of antibiotics. Some people recover this bacteria in their GI tract after antibiotics, some don’t. This is the Gastrointestinal form of hyperoxaluria. There is also a genetic type of problem with oxalates called Hyperoxaluria Type 1, Type 2 and a third form Type 3. I have the minor allele for AGXT, primary Hyperoxaluria Type 1 and the gene works at about 50% of normal. Now just having the minor allele which consist of 2 snps in the homozygous state, is not enough to create the really bad version of this. For it to show up in childhood or early adulthood it would require these 2 snps and a third pathogenic snp which was not tested in 23 and Me’s test. I don’t believe I have that situation or I would have been dead with trashed kidneys long ago, although it can manifest in later years up to age 40 or 50. Still I do think it affects me systemically. I have always had a natural aversion to high oxalate foods but in my attempt to “eat healthier” I started to incorporate some of these foods into my diet. Still the amount was much lower than most people eat. A significant step in recovering my health involved going back to the level of oxalate intake that I had eaten for years and scrapping a preconceived ideas about healthy food and eating. What a change! I had been struggling with healing the GI tract after 2 years of working on it, also struggling with the hypoglycemia which was really unstable at this time. Both situations improved dramatically when I dropped the oxalate intake down to a low to medium level. If you have problems with not being able to heal the GI tract, repeat Urinary tract infections (UTI) or issues with what seems like repeat UTI’s but nothing shows on the test, Vulvodynia, Interstitial Cystitis, Autism related GI problems, chronic kidney stones you might check out Oxalates. There is an Oxalate researcher called Susan Costen Owens who has a Yahoo group called “Trying Low Oxalates” that has the most extensive and tested list on oxalates. It is not an easy diet and it can take some time to get the oxalate levels down as the elimination process can cause problems if it is applied to quickly. It can have some rather unpleasant side effects when your body starts pulling the stored oxalates out of your system, especially when done too fast. It takes time but oxalates are a toxin and can affect many body systems, even eyes and skin.

So you might ask, “What is left to eat?” Quite a lot actually, kinda like we used to eat before fast food and all the overly processed foods that line the store shelves now. I shop the outside of the store, I eat great cuts of meat about the size of my palm, I eat limited fruit because of the sugar levels but do eat veggies, especially the root veggies as I need the carbs but not the high sugar content. I also use gluten free grains which I wish I did not rely on so heavily but they have the kind of carbs that work best and slowest, rice and potato are my major starches. I have an occasional salad, some Avocados. I bake my own gluten free english muffins made from a mix of gluten free grains but with a much higher protein content than the usual starchy gluten free, nasty breads which cost a fortune and taste horrible. Mine are almost like a whole grain bread, soft and moist. I bring my own food and use these for sandwiches every day at lunch as I have only a microwave at work and can’t eat out at most restaurants. I drink only water and coffee, lots of water.

June 21, 2015 - I just finished designing my Coat of Arms for the Edelen (Edlin) family. Although I have several family lines that go back to nobility in early Europe, this family line is the cleanest and most direct. It appears that most, if not all, Edlins - Edelens in America are related to an original descendant, Richard Edelen, who immigrated to the Colonies in 1635 and lived in Maryland. This exercise of designing a Coat of Arms posed an interesting dilemma. Which family line do you choose? Although my mothers side of the family has more lines descending from nobility, surprisingly it was my fathers side that provided a clear direct line of male descendants that would most qualify for a coat of arms. This line goes directly to my paternal grandmother. I did not really know her as she died when I was 6 years old and I never knew my paternal grandfather or have even seen pictures of him. This has been a big driving force for the genealogy research. This family was split up when my father was a child and the children were all adopted into foster families. This in large part was due to the effects of my grandfather having been in the war as well as the repercussions of the Great Depression. They were divorced shortly after the 4th child had been born.
This Coat of Arms that I present is not official but is made of the elements from the Coat of Arms supposedly presented to Crolian Edelen, who has now passed but some of his research is recorded by other cousins and his own posting on the web. I have attempted to do it in the spirit and by the letter of heraldic design. It will only be on the Edelen/Edlin page and the main page of this website.

May 16th, 2015- Calling all ancestors
I have tendency toward philosophic and metaphysical musings at times. Having often heard of the relationship that many indigenous cultures around the world have with their ancestors and how they keep in touch with the deceased family members, it just seemed a little too much like talking to ghosts for me. This is just something that I could not relate to, especially since I only had one ancestor that I could call on if so needed, until recently. My grandmother on my mothers side was the only blood relative I knew of and she just passed on a few years ago. The grandfather I knew, although not related was very much a grandfather and I knew nothing of my fathers parents. I have vague memories of his mother when I was 6 years old, at her funeral. I knew nothing of his father as their family had been split up when my father was young, each of the children being adopted out. In my fathers case he was taken in by people looking for help with their farms (slave labor). The conditions were dismal to say the least and my father ran away a few times, eventually being adopted by his new step father when his mother remarried.
During my studies in genetics, looking for these problem causing genes, I actually came across some SNP’s that I could identify some ancestors with, not the specific person or time but the region they came from. I have some variants only found in Africa even though I am mostly European British and Irish and it was very strange to run into these SNP’s that don’t exist in the Euro population and know I was looking at what a specific ancestor left. There were some with founder mutations from Portugal, some only found in Italy.
This new awareness got me thinking about the individual gentetic contributions, for better or worse, of all these ancestors and this fueled my curiosity even more to do the family genealogy. Where did these genes come from and what people gave them to me?
In looking at the mosaic of genes it occurred to me that I now had ancestors to call on, on a genetic level. Their strengths and weaknesses are a very real part of me and I can call on those strengths, try to work with the weaknesses on a cellular level. On a spiritual level, they have woven themselves into my makeup, I am them and they are me, I will carry them with me always.

April 18th, 2015- Since someone destroyed the Sizemore line that was in FamilySearch.org, I took it upon myself to rebuild it and after compiling multiple sources, as reputable as I could find I rebuilt it without the ton of errors that were there before. It was a mess and needed rebuilt.

March 21st, 2015, added files to LaForce family page.